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Purpose Radiation necrosis (RN) is an important complication of radiation therapy (RT) and is challenging to assess radiographically because lesions are prone to inconsistent delineation, often necessitating intracranial surgery to obtain a diagnosis. This study evaluated how established deep learning segmentation mode...
Progress in neuro-oncology drug development has been slower than the pace of biological discovery, and trial design is increasingly recognized as a central contributor to this gap. Traditional trial paradigms, largely developed for systemic malignancies, face distinct challenges when applied to central nervous system (...
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