Open access
Sep 2026
A passive protein environment offsets RNA folding energetics in cells
This work combines single-molecule FRET with Xenopus oocyte extract with Xenopus oocyte extract to measure RNA folding and duplex formation under cell-like conditions and identifies a passive protein-mediated mechanism as a key contributor to cellular RNA folding.
M. Todisco, F. Boskovic, A. Jain
· bioRxiv · 0 citations