Sep 2026
Cellular and molecular mechanisms determining allogeneic CAR T cell rejection and expansion.
High frequencies of pre‑existing, recipient-derived alloreactive CD8+ T cells mediated rapid CAR T rejection in non-expanders and effector-like features, rather than stem/central memory programs, drove robust clonal CAR T expansion consistently across expanders.
A. Jallouk, Zhong-Qi Ge, V. Kaimal et al.
· Cancer Discovery · 0 citations