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Open access Sep 2026

The impact of statin therapy on amputation risk in patients with diabetic foot infection: a retrospective cohort study from Jordan

Background Diabetic foot infection (DFI) is a major cause of non-traumatic lower-limb amputation and is associated with poor survival outcomes. Identifying therapies that reduce progression to amputation is critical. Objective To evaluate the association between statin therapy and risk of amputation in patients with DF...

Jana Abdallah, M. Ababneh, A. Jarab et al. · 0 citations
Open access Sep 2026

Developing Growth Reference Curves for Jordanian Children and Adolescents: A Comparative Analysis with WHO Growth Standards and References

Background: Growth standards and growth references serve different purposes. The WHO Child Growth Standards for ages 0–5 years describe growth under specified optimal conditions, whereas the WHO 5–19-year curves are a reference reconstructed from historical NCHS data. This study aimed to develop sex-specific growth ref...

Walid A. Al-Qerem, Ruba Zumot, A. Jarab et al. · 0 citations
Review Open access Sep 2026

Advancing interprofessional collaboration: exploring physicians’ perceptions, preferences, and barriers regarding pharmacists’ roles in Jordan

ABSTRACT Background Interprofessional collaboration is crucial for improving healthcare delivery and addressing workforce challenges. Physician-pharmacist collaboration enhances patient care, improves medication management and health outcomes. While patients’ perspectives have been studied, physicians’ views in Jordan...

Zelal Kharaba, K. Alzoubi, Mai Riziq et al. · 0 citations
Review Open access Sep 2026

From ADA positivity to clinical decision: a context-of-use framework for reflex testing, sampling frequency and stopping rules in immunogenicity assessment.

A context-of-use framework for immunogenicity assessment is proposed for ADA testing, which should be designed around decisions it is expected to support, including pharmacokinetics/, pharmacodynamics (PK/PD) interpretation, efficacy, safety, labeling, dose selection, treatment interruption, and development progression...

Ahmad Z. Al Meslamani, A. Jarab, H. El Sharu et al. · 0 citations
Review Open access Aug 2026

Digital twins in precision pharmacotherapy: emerging applications, challenges, and future directions

Digital twin technology, defined as dynamic digital models that represent individual patients, is emerging as a promising paradigm in precision pharmacotherapy. The integration of pharmacokinetic and pharmacodynamic (PK/PD) modeling, clinical data, genomic information, and real-time patient monitoring enables digital t...

A. Jarab, Walid A. Al-Qerem, Hamza Jarab et al. · 1 citation
Review Aug 2026

Developability-by-design for bispecific antibodies in discovery: combining computational prediction and early screening for candidate selection.

This structured narrative review examines literature identified in PubMed/MEDLINE, Embase, Scopus and Web of Science from database inception, supplemented by citation tracking to find developability risks beyond those encountered with conventional monospecific antibodies.

Ahmad Z. Al Meslamani, A. Jarab, Khadeijah Ahmed Al Marshoodi · 0 citations

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