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Author

A. Jaźwa-Kusior

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Open access Oct 2026

Endothelial senescence impairs efferocytosis and alters macrophage responses: insights into APP-CD74 signaling

Endothelial cell senescence contributes to vascular aging and chronic inflammation, yet its impact on endothelial–macrophage interactions remains poorly understood. Here, we combined functional assays, global proteomics, 3D co-culture spheroid models, and single-cell transcriptomics to elucidate how senescent end...

K. Sarad, W. Waluś, Gabriela Burda et al. · 0 citations

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