Microbiome-metabolome multi-omics biomarkers for infectious disease prognosis: Current evidence, AI-driven integration, and translational challenges.
Current evidence supports the potential of microbiome-metabolome biomarkers as complementary prognostic tools rather than routine clinical diagnostics, but most of the available evidence remains exploratory and is hampered by cohort heterogeneity, small sample sizes, cross-sectional study designs, batch effects, limite...