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Author

A. K. Kalia

2 papers indexed here

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Review Open access Sep 2026

A Framework for NGN1-Induced Sensory Neuron Differentiation for Disease Modelling and Drug Screening

Background Neuropathic pain is a burdensome, difficult-to-treat, and highly heterogeneous condition with limited therapeutic options, underscoring the need for robust and reproducible human disease models. Human induced pluripotent stem cell (iPSC)–derived sensory neurons provide a promising platform for patient-specif...

Anika Neureiter, Marlene Menke, Veronica Donde et al. · 0 citations
Open access Sep 2026

In vitro programming and pseudounipolarization of human iPSC-derived sensory neurons

Ectopic expression of NGN1, BRN3A and ISLET1 (NBI) from a safe harbor locus in induced pluripotent stem cells (iPSCs) yielded robust differentiation into functional sensory neurons (iNBI-SNs) within seven days. Single nucleus transcriptomics identified peripheral sensory neuron profiles of nociceptors and mechanorecept...

Pascal Röderer, A. C. Costa, M. Lürkens et al. · 0 citations

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