Open access
Oct 2026
Integration of single cell omics with biobank data discovers allele-specific trans effects of SREBF1 on adipocyte expression of nearly 100 genes
The heritability of epigenetic sites around SAT adipocyte marker genes is enriched for abdominal obesity, and that these cell-type markers are also enriched for central pathways of adipocyte function, indicating widespread cell-type level cis-type level trans effects on highly common CMDs.
M. G. Sukhatme, A. Kar, Seung Hyuk T. Lee et al.
· Genome Medicine · 0 citations