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A. Karam

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Open access Sep 2026

Multilayered extracellular matrix–derived scaffolds direct progenitor cell differentiation in vitro and osteochondral-tissue formation in vivo

Osteochondral repair requires restoration of zonally organised articular cartilage and subchondral bone, yet translatable implants rarely reproduce this spatial complexity. Here, we developed an acellular multilayer scaffold comprising a superficial 2% (w/v) articular cartilage extracellular matrix (AC-ECM) phase, an i...

G. Gonnella, O. Strong, V. M. Sularea et al. · 0 citations
Open access Jul 2026

Tunable Sol-Gel Transition in Poloxamer Blends for Injectable Osteoarticular Applications.

The results show that careful selection and optimization of poloxamer blends allow tailoring material properties for specific biomedical functions, and make them practical for further development in injectable biomaterials and drug delivery systems for osteoarticular repair.

M. Tuszyńska, J. Skopińska-Wiśniewska, Kaoutar Chattahy et al. · 0 citations

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