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Author

A. Karan

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Open access Sep 2026

Multifocal Initiation of Spreading Depolarization by Generalized Tonic-Clonic Seizures

Epileptic seizures are self-terminating events, yet the precise mechanisms underlying their cessation and the subsequent postictal suppression remain incompletely understood. Spreading depression (SD)—a traveling wave of intense depolarization and electrical silence—has emerged as a potential mechanism of focal seizure...

M. Smirnova, A. Karan, T. Medvedeva et al. · 0 citations

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