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Author

A. Keepanasseril

2 papers indexed here

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Review Open access Sep 2026

Maternal complete heart block in pregnancy: A systematic review and meta-analysis

Background Complete heart block (CHB) is an uncommon bradyarrhythmia complicating pregnancy, posing challenges to the treating team. Objective To evaluate the maternal outcomes, other cardiac complications, and pregnancy outcomes among pregnant women with CHB and compare these outcomes among those managed with and with...

Shabnam Kottummal, Varun Muppidi, Yavanasuriya Jeganathan et al. · 0 citations
Open access Aug 2026

Factor IX gene variants may influence the pharmacokinetic profile of patients with hemophilia B treated with FIX-Fc or N9-GP extended half-life FIX concentrates.

BACKGROUND FIX exhibits significant extravascular distribution and binds type IV collagen in the subendothelial extracellular matrix in the extravascular space, which influences its function and pharmacokinetics (PK). Many hemophilia B patients carry missense F9 mutations that produce circulating, dysfunctional FIX pro...

D. Matino, Z. Al-Housni, B. Samelson-Jones et al. · 0 citations

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