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Author

A. Khanfir

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Review Open access Aug 2026

Efficacy and safety of adjuvant CDK4/6 inhibitors in hormone receptor-positive, HER2-negative early breast cancer: Updated evidence from a systematic review and meta-analysis.

IntroductionThe long-term survival impact of adding CDK4/6 inhibitors to adjuvant endocrine therapy for hormone receptor-positive, HER2-negative (HR+/HER2-) early breast cancer remains a subject of active evaluation. We performed an updated meta-analysis incorporating the mature efficacy and survival data to comprehens...

W. Ben Kridis, A. Khanfir · 0 citations
Open access Aug 2026

Comprehensive Genomic Profiling Reveals the Mutational Spectrum and Clinical Significance of BRCA1/2 and Other Cancer-Susceptibility Genes in Breast Cancer Patients from Southern Tunisia

This study investigated germline genetic variants in 165 Tunisian breast cancer patients using targeted next-generation sequencing of a multigene cancer panel to identify pathogenic or likely pathogenic variants in BRCA1 and BRCA2 genes and identified P/LPVs in other genes.

N. Ammous-Boukhris, Rania Abdelmaksoud-Dammak, W. Ben Kridis et al. · 0 citations

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