Jul 2026
Furin sustains tumor-promoting signals in KRAS- and BRAF-mutated colorectal cancer by engaging the TGF-β1-COX-2 axis in a reciprocal regulatory network
Cutting Furin activity slowed tumor growth, improved the response to common chemotherapy drugs, reduced blood vessel formation, and increased the presence of cancer-killing immune cells are found.
Yiyang Liu, G. Siegfried, S. Pernot et al.
· Oncogene · 0 citations