Author

A. Kraus

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Open access Aug 2026

Emotional processing biases in the longitudinal course of major depressive disorder.

Negative biases in emotional processing are central to cognitive models of Major Depressive Disorder (MDD), yet it remains unclear whether negatively biased valence attribution covaries with depressive symptoms or represents a more stable vulnerability. In this longitudinal study, we examined emotional valence ratings...

Katharina Hierl, Liane Wollweber, H. Lemke et al. · Journal of Affective Disorde... · 0 citations

Open access Sep 2026

Illness Severity and Longitudinal Gray Matter Volumes Among People With Major Depressive Disorder

Key Points Question Are gray matter volume (GMV) trajectories over the long-term course of major depressive disorder (MDD) associated with cumulative or acute illness severity? Findings In this 10-year case-control study including 206 participants, fronto-limbic GMV changes were significantly associated with individual...

A. Kraus, J. Goltermann, T. Borgers et al. · JAMA Network Open · 0 citations

Open access Aug 2026

The timeline of brain aging in major depression: A prospective study from before first-onset to established illness

Major depressive disorder (MDD) has been associated with accelerated structural brain aging, yet whether this reflects a pre-existing neurobiological vulnerability, a dynamic acute state effect, or an accumulating biological residual remains unresolved. Across two longitudinal cohorts (N=3220), including a unique sampl...

M. Konowski, A. Kraus, J. Goltermann et al. · medRxiv · 0 citations