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Author

A. Kremling

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2 papers indexed here

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Open access Sep 2026

Mechanistic modeling of bacterial translation initiation across growth conditions

Translation frequency in bacteria depends on how ribosomes, mRNAs, and initiation factors are allocated across growth conditions. Here, we developed a mechanistic ODE-based model of Escherichia coli translation that represents initiation, elongation, termination, and coupled auxiliary processes. Growth-dependent abunda...

Jia-Hui Qin, A. Kremling · 0 citations
Open access Sep 2026

Characterisation of metabolic burden in Pseudomonas putida reveals precursor limitation in heterologous lycopene production

Together, these findings provide a systematic framework for distinguishing constraint layers and guiding the optimisation of heterologous terpenoid production systems and show that regulatory design shaped pathway performance.

Carina Meiners, Lucas Hermann, Mishela Stoja et al. · 0 citations

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