Author

A. La Russa

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Review Open access Oct 2026

The NLRP3 Inflammasome Across the AKI–AKD–CKD Continuum: Mitochondrial, Epigenetic and Endocrine–Metabolic Regulation

The NLRP3 inflammasome has emerged as a potential molecular link between cellular stress, sterile inflammation, and progressive kidney damage. This review critically examines canonical, non-canonical, and mitochondrial mechanisms of NLRP3 regulation across the acute kidney injury (AKI)–acute kidney disease (AKD)–chroni...

D. La Russa, S. Bossio, A. La Russa et al. · International Journal of Mol... · 0 citations

Open access Sep 2026

Epigenetic aging and autosomal methylation remodeling in Anderson-Fabry disease.

Preliminary evidence is provided that autosomal epigenetic remodeling and biological aging acceleration may contribute to phenotypic heterogeneity in AFD, and DunedinPACE may capture aspects of the cumulative systemic burden associated with pathogenic GLA variants.

M. A. Aceto, Ersilia Paparazzo, Gemma Antonucci et al. · Experimental Gerontology · 0 citations