Author

A. Lam

2 papers indexed here

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Review Open access Sep 2026

Copper, cuproptosis, and cancer: biology concepts of a novel cell death

Copper is an essential trace element required for mitochondrial respiration, redox regulation, iron metabolism, and cellular signalling, but excessive or mislocalised copper can be cytotoxic. Cuproptosis is a recently identified form of regulated cell death in which copper binds to lipoylated mitochondrial proteins, pr...

R. Eshraghi, N. Hosseini, Mohammad Sepehr Yazdani et al. · Apoptosis · 0 citations

Sep 2026

A phase II trial of chemotherapy-free neoadjuvant camrelizumab plus apatinib for resectable HNSCC: pathological response and vascular-immune crosstalk.

PURPOSE To evaluate the efficacy, safety, and tumour microenvironment remodelling of neoadjuvant camrelizumab plus apatinib in resectable head and neck squamous cell carcinoma (HNSCC; stage II-IVA). MATERIALS AND METHODS In this single-arm, exploratory phase II trial (ChiCTR2100051989), 41 patients with resectable HN...

Ya-Qiong Jie, Zhuo Chen, Li-Huang Chen et al. · Clinical Cancer Research · 0 citations