Phage-Derived Depolymerase-Functionalized Coatings Prevent Staphylococcal Biofilm Formation.
Biofilm-associated infections caused by Staphylococci remain a major challenge in the context of biomedical implants due to their tolerance to antibiotics and resistance to host defenses. Here, we report the identification of a novel phage-derived depolymerase (DPO2) targeting staphylococcal biofilms and its integratio...