PRO-C6 and endotrophin are associated with cardiac remodelling and adverse outcomes in HFpEF: data from the prospective NETDiamond cohort
Heart failure with preserved ejection fraction (HFpEF) is characterized by extracellular matrix (ECM) remodelling and fibrosis, but clinically useful circulating biomarkers reflecting these processes remain limited. To assess whether circulating ECM-derived biomarkers (PRO-C3, PRO-C6 and endotrophin) are a...