Author

A. Lesman

2 papers indexed here

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Preprint Sep 2026

Local Strain-Dependent Anisotropy in Fibrous Networks

Cells in connective tissues reside within the extracellular matrix (ECM), which consists of a fibrous mesh that exhibits non-linear strain-stiffening behavior, driven by a transition from bending-to-stretching-dominated deformation. While bulk rheology captures macroscopic mechanical properties, cells actively sense an...

Yoni Koren, S. Goren, O. Tchaicheeyan et al. · 0 citations

Preprint Sep 2026

Mechanical Clustering of Cells via the ExtraCellular Matrix

Tissues are composites of living cells and extracellular matrix (ECM), that jointly determine their unique mechanical behavior. Here, we experimentally demonstrate that contractile cells remodel the ECM by generating long-range bands of aligned and densified fibers that mechanically couple cells into multicellular clus...

Ran Glinowiecki, S. Goren, O. Tchaicheeyan et al. · 0 citations