Open access
Oct 2026
Click-to-Release Reactivity of Quaternary Anilinium Tetrazines Enables Cascade Assembly of Multifunctional Biomolecular Scaffolds.
Click chemistry has evolved from its origins in forming covalent connections to also include breaking bonds, cleaving linkers, and liberating cargo, creating broad applications in chemical biology and biomedicine. The reaction sequences that drive these tools are complex, and thus prone to an array of dead-end intermed...
Markus Staudt, C. Poulie, A. Löffler et al.
· Angewandte Chemie · 0 citations