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Structural connectivity partially mediates the seizure-survival association, suggesting preserved network architecture may contribute to why seizure patients survive longer, though the majority of the effect operates through other pathways.
Cross-sectional findings link cognitive impairment in epilepsy to a reduced capacity for adaptive hub reorganization rather than to pathology alone, and may offer an objective imaging biomarker to complement neuropsychological testing, aid identification of patients at risk for cognitive decline, and inform prognostic...
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