Heart failure with preserved ejection fraction (HFpEF) represents a predominant heart failure phenotype characterized by intricate pathophysiology and an escalating global prevalence. Beyond classical hemodynamic disturbances, emerging evidence identifies mitochondrial dysfunction as a central mechanism in HFpEF pathog...
Ying An, Cong-Hui Shang, A. M. Abd el-Aty et al.· The Journal of Cardiovascula...· 0 citations
Biological systems maintain functional integrity under environmental stress through tightly coordinated signaling networks, yet the mechanisms that preserve signal fidelity in the presence of stochastic oxidative and ionic fluctuations across taxa remain incompletely understood. Although redox regulation, coupling betw...
Mohamad Warda, Merve Bolat, S. Tekin et al.· Plants· 0 citations
The gut–skin axis represents a bidirectional communication network linking the gut microbiota, microbial metabolism, immune regulation, and skin physiology. Natural bioactives derived from dietary plants, mushrooms, fermented foods, marine resources, and functional ingredients may influence skin health through both dir...
Jih-Ye Lee, Hae-Jin Park, Eun-Mi Ahn et al.· Nutrients· 0 citations
Nonalcoholic fatty liver disease (NAFLD) is characterized by dysregulated hepatic lipid metabolism and oxidative stress under chronic metabolic overload. AMP-activated protein kinase (AMPK) is a central regulator of metabolic and redox homeostasis; however, immune-derived signals that coordinate metabolic adaptation in...
Min Kyung Pyo, Jun Hwi Ko, Do-Su Lim et al.· International Immunopharmaco...· 0 citations
Background: Alterations in glutamatergic homeostasis have been implicated in Alzheimer’s disease, but the relationship between total hippocampal tissue glutamate and Alzheimer-like molecular alterations remains unclear. This study evaluated the early neuroprotective potential of gentisic acid (GA) and erucic acid (EA)...
Ibrahim Gecili, M. Ertuğrul, I. Okkay et al.· Pharmaceuticals· 0 citations
To address environmental concerns associated with nondegradable plastics, biodegradable active packaging materials have gained attention. This study developed konjac glucomannan-chitosan quaternary ammonium salt films incorporating Pickering emulsions stabilized by whey protein isolate (WPI)-ellagic acid (EA) complexes...
