Author

A. Mahmoud

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Oct 2026

Probiotics Attenuate AlCl₃-Induced Alzheimer's Disease via Gut-Brain Axis Modulation and Suppression of NF-κB/NLRP3 Neuroinflammation.

Disruptions along the brain-gut-microbiota axis significantly contribute to Alzheimer's disease (AD) pathogenesis. This study evaluated the therapeutic potential of a multi-strain probiotic mixture in mitigating cognitive decline, neuroinflammation, and amyloid pathology in an AD rat model. In the present study, after...

Asmaa M. Elfiky, Eman M. Shahy, A. Mahmoud · Physiology and Behavior · 0 citations

Open access Aug 2026

SULFORAPHANE SUPPRESSES HEPATOCELLULAR CARCINOMA IN MICE VIA ACTIVATING p53, MITIGATING OXIDATIVE STRESS, AND INHIBITING ANGIOGENESIS.

SF decreased the number of tumor nodules and ameliorated HCC by activating p53 expression, inducing apoptosis, and inhibiting proliferation, oxidative stress, and angiogenesis, and support further translational evaluation of SF as a potential therapeutic agent for HCC.

Kholoud A. Omran, Yomna I. Mahmoud, A. Mahmoud et al. · Experimental oncology · 0 citations