Open access
Jul 2026
Tumor microenvironment-mediated interactions between macrophages and cancer cells define immunoregulatory transcriptional programs.
It is demonstrated that the non-cellular tumor microenvironment preserved in PDSs is sufficient to drive coordinated transcriptional programs in both macrophages and cancer cells, and to guide future strategies targeting macrophage-cancer cell crosstalk in breast cancer.
Göran Landberg, Mikaela Ståhlberg, E. Frisk et al.
· Biomedicine & pharmacotherap... · 0 citations