Author

A. Mason

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Open access Sep 2026

Scorpion venom-derived Opis16a shows potent membrane-destabilising Gram-negative activity and promising in vivo topical efficacy

It is shown that Opis16a rapidly kills Gram-negative bacteria by targeting and disrupting their membranes, with strong bacterial selectivity over HaCaT and HepG2 cell lines.

Mandelie van der Walt, C. Oosthuizen, A. Mason et al. · npj Antimicrobials and Resis... · 0 citations