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Open access Oct 2026

Single‐Cell Integration of Mouse Models of Autism Reveals Conserved Transcriptomic Signatures of Excitatory‐Inhibitory Imbalance and Glial Dysfunction

ABSTRACT The etiological heterogeneity of autism spectrum disorder (ASD) complicates identifying core molecular mechanisms. We systematically integrated scRNA‐seq data from 11 diverse genetic and environmental mouse ( Mus musculus ) models, encompassing > 300,000 cells across multiple brain regions and developmental st...

J. Nani, Victor J. Duque, A. Muotri et al. · 0 citations

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