Granulomatous lymphocytic interstitial lung disease (GLILD) is a non-infectious complication of common variable immunodeficiency (CVID) entailing increased morbidity and mortality. The pathogenesis of GLILD remain unclear, and optimal treatment strategies are lacking. We aimed to highlight GLILD pathogenesis and id...
M. S. A. Fraz, A. Michelsen, H. Hol et al.· ERJ Open Research· 0 citations
It is found that CVID is associated with extensive, cell type-specific epigenetic remodelling, particularly in T cells, and Wnt signalling emerges as a recurrently altered pathway across DNA methylation, circulating proteins and gene expression, supporting Wnt-related mechanisms as a potential contributor to CVID immun...
Vegard Myhre, Ming-Yi Yang, Mari Kaarbø et al.· Frontiers in Immunology· 0 citations
This discovery study suggest that LDS could represent a particular inflammatory subgroup of HTAD patients potentially reflecting the involvement of Th17 and platelet related mechanisms in the progression of TAA.
B. E. Seim, Y. Khan, Margrethe Flesvig Holt et al.· Scandinavian Cardiovascular...· 0 citations
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