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A. Minn

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Open access Jul 2026

Targeting a cancer cell Interferon-TBK1 signaling axis attenuates inflammatory memory mediated resistance to immune checkpoint blockade 2257735

It is observed that ex vivo JAKi and TBK1i treatment, in a cancer cell intrinsic manner, induces a more stem-like CD8 T cell response following ICB, possibly through improved interactions with myeloid cells.

Nathan Dangle, Jingya Qiu, D. Ye et al. · 0 citations

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