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Author

A. Miroshnikov

1 paper indexed here

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Aug 2026

Activity of natural single nucleotide variants of human alkyladenine DNA glycosylase AAG R145H, G163S and R197C involved in DNA binding.

Alkyladenine DNA glycosylase (AAG) is a critical enzyme in the base excision repair (BER) pathway that safeguards genome integrity by removing structurally diverse alkylated and deaminated purine lesions from DNA. It serves as a primary defense against alkylation-induced mutations, which are linked to cancer developmen...

O. A. Kladova, T. E. Tyugashev, A. Miroshnikov et al. · 0 citations

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