Open access
Aug 2026
Core activation program and selective regional responsiveness of microglia during aging and parabiosis.
Aging is associated with immune dysregulation in the brain and is the greatest risk factor for many neurodegenerative diseases. Rejuvenation interventions can mediate beneficial effects. Microglia are major contributors to neurodegenerative disease progression; however, the molecular changes underlying brain aging and...
H. Naz, Nannan Lu, Caroline C. Escoubas et al.
· Cell Reports · 0 citations