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Author

A. Mooyaart

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Open access Sep 2026

PLA2G2D in tumour-draining lymph nodes regulates anti-tumour immunity

In-depth spatial profiling identifies PLA2G2D as a TDLN-centred targetable immune checkpoint for cancer immunotherapy and identifies a specific population of macrophages that express high levels of the enzyme PLA2G2D in tumour-draining lymph nodes that is associated with poor prognosis in patients.

A. van Krimpen, Julie Y. Huang, Mike Eterman et al. · 0 citations
Open access Jul 2026

Comprehensive molecular characterization of cutaneous squamous cell carcinoma reveals determinants of metastatic progression

A 23-gene expression signature was built to predict metastasis from primary cSCC tissue, and this findings provide the most detailed molecular portrait of cSCC to date and establish an assay for risk stratification suitable for clinical implementation.

B. Rentroia-Pacheco, Harsh Sharma, L. Pozza et al. · 0 citations

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