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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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A. N. Castagno

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Open access Aug 2026

Cholesterol restores cortico-striatal synaptic connectivity in Huntington's disease through BDNF-TrkB signalling, supporting a role for cholesterol pathways implicated by human genetic modifier studies.

It is shown that increasing cholesterol availability prevents synapse loss and restores cortico-striatal connectivity in HD models, establishing cholesterol as a critical regulator of cortico-striatal synaptic integrity in HD and supporting targeting cholesterol homeostasis as a therapeutic strategy to restore synaptic...

Allegra Lenci, Michela Villa, Andrea Scolz et al. · 0 citations

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