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A. N. Mendes

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Open access Jul 2026

Integrative Network Pharmacology and ADMET Modeling Reveal the Multitarget Therapeutic Potential of Geraniol

Findings confirm geraniol's multitarget and pleiotropic nature, highlighting its potential as a therapeutic candidate for inflammatory, metabolic, and neurodegenerative disorders and provides a robust mechanistic rationale for future in vitro and in vivo validation.

Mateus Henrique de Almeida da Costa, Lívia Alves Filgueiras, A. N. Mendes · 0 citations
Open access Aug 2026

A mechanistic approach about oxidative, mutagenic, and cytotoxic effects of an organotellurane.

RF07 exhibits antiproliferative action on animal cells, high toxicity on Artemia salina nauplii, as well as clastogenic effects on growing roots.

Felipe Emannuel Alvino de Jesus, Octávio Augusto de Carvalho Maia, Antonielly Campinho Dos Reis et al. · 0 citations
2026

Computational Study of Enzyme Inhibition.

Key computational techniques, including molecular docking, molecular dynamics, and QSAR modeling, which enhance the accuracy and efficiency of drug design are explored, emphasizing their role in accelerating drug development and improving therapeutic outcomes.

Francisco das Chagas Pereira de Andrade, Mateus Henrique de Almeida da Costa, A. N. Mendes · 0 citations

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