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Author

A. N. Siddique

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Sep 2026

Exploring the Role of Positive Selective Sites in Enhancing Structural Stability and Functional Efficiency of Human Lipase A.

Lysosomal acid lipase (LAL), encoded by the LIPA gene, is essential for lipid metabolism, and its deficiency causes Wolman disease and cholesteryl ester storage disease. Understanding the structural determinants of LAL stability and function is crucial for protein engineering and therapeutic development. We integrated...

H. Mahmood, Tariq Mahmood, Faisal Nouroz et al. · 0 citations

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