It is demonstrated that repeated environmental heat stress induces coordinated neuroendocrine, vascular, immune, and metabolic adaptations characterized by activation of heat shock pathways, immune remodeling, and endothelial activation that precede cardiovascular dysfunction.
Hibah Husain, Samantha A. McFall, M. Malovichko et al.· The FASEB Journal· 0 citations
It is concluded that kinetin and zinc, alone and their combination show neuroprotective effects in TBI by activating Nrf-2 anti-oxidant defence and inhibiting NLRP3-NF-ԟB pathways.
Shivani Agarwal, M. Shahrukh, Divya Vohora et al.· Naunyn-Schmiedeberg's Archiv...· 0 citations
This review breaks down the pathways triggered by immune cells activation (neurotoxic microglial phenotype) and majorly focusing over the NLRP3 inflammasome neuroinflammation pathway, exploring the promising therapeutic potential of specific bioactive phytochemicals, repurposed and novel synthetic drugs/agents to shut-...
Devesh Yaduvanshi, Rishabh Aggarwal, Sameeya A et al.· Expert opinion on therapeuti...· 0 citations
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