Abstract Background Pregnancy and the postpartum period constitute a high-risk window for the emergence of depressive symptoms. Peripartum depression (PPD) affects around 17% of women worldwide [1] and remains substantially underdetected, with clinically meaningful consequences for maternal functioning, mother-infant b...
B. Vai, L. Fortaner-Uyà, M. Shahisavandi et al.· International Journal of Neu...· 0 citations
Social behaviour is a heritable trait linked to well-being and mental health, yet it varies across social context, including social domains, informants and development, which may shape its underlying genomic architecture. Here, we conducted a genome-wide meta-regression meta-analysis of social behaviour from infancy to...
L. de Hoyos, Fenja Schlag, Sanjeevan Jahagirdar et al.· Nature Human Behaviour· 0 citations
Most MPSs are better characterised as research tools at an early stage of development rather than clinical tools, and are highlighted as research tools at an early stage of development rather than clinical tools.
I. Schuurmans, S. Defina, A. P. C. Hermans et al.· The Lancet Child & Adolescen...· 0 citations
Background. Cord blood DNA methylation profile scores (MPSs) based on genetic and pre-/perinatal risk factors for neurodevelopmental conditions (NDCs) may capture downstream biological effects and help understand how combined exposure signals contribute to NDC risk. Methods. Using data from two longitudinal birth cohor...
Elena Isaevska, Rosa H. Mulder, I. Schuurmans et al.· medRxiv· 0 citations
It is found that genomic associations with cord blood DNAm are stronger and more widespread than prenatal exposures, although typically, the prenatal exposome explains additional variation in DNAm beyond genetic influences.
Rosa H. Mulder, Elena Isaevska, C. Cappadona et al.· bioRxiv· 0 citations
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