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Author

A. Nussler

3 papers indexed here

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Open access Oct 2026

Adiponectin-enriched liver-derived ECM attenuates fibrogenic features of activated hepatic stellate cells in a multicellular 3D model

Adiponectin (ADPN), an adipocytokine expressed in multiple tissues including the liver by quiescent hepatic stellate cells (HSCs) has recognized antifibrotic properties. However, most studies rely on simplified 2D systems that fail to capture the liver microenvironment. This study investigated the antifibr...

B. Sadri, Z. Hashemian, Mustapha Hassan et al. · 0 citations
Open access Aug 2026

Clinically Interpretable Machine Learning for Glycemic Risk Screening in Trauma Patients

Undiagnosed diabetes and prediabetes are common among trauma patients and increase perioperative complication rates, yet routine glycemic screening at hospital admission is rarely performed. We compared 10 supervised machine learning (ML) algorithms for early detection of impaired glucose metabolism in 1789 trauma surg...

M. Tombaz, A. Nussler, Engin Tercan et al. · 0 citations
Review Open access Aug 2026

Epigenetic Regulation of Liver Fibrosis: Mechanisms and Therapeutic Implications

This review summarizes the principal epigenetic changes involved in HSC activation, initiation/progression of liver fibrosis, and discusses recent interventions designed to modulate these epigenetic changes.

M. J. Tavaf, M. E. Varkiani, Saeid Abroun et al. · 0 citations

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