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A. Obi

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Open access Aug 2026

Ameliorative Effects of Ethanolic Abelmoschus esculentus (Okro Leaf) Extract on Phenylhydrazine-Induced Haematological and Splenic Alterations in Wistar Rats

Ethanolic A. esculentus leaf extract ameliorated PHZ-associated haematological alterations and improved feed intake in Wistar rats, suggesting potential protective activity against PHZ-induced toxicity.

E. O. Nweke, Mmesoma Charity Chukwunwike, A. Obi et al. · 1 citation
Open access Aug 2026

Biochemical and Histological Effects of Ethanolic Solanum lycopersicum Fruit Extract on Aspirin-Induced Hepatotoxicity in Adult Male Wistar Rats

Ethanolic S. lycopersicum fruit extract was associated with histological evidence of hepatic regeneration following aspirin exposure, although biochemical findings did not demonstrate consistent hepatoprotection.

E. O. Nweke, E. Okoye, A. Obi et al. · 0 citations
Open access Aug 2026

Gastroprotective Effects of Ethanolic Leaf Extract of Abelmoschus esculentus on Phenylhydrazine-Induced Gastric Toxicity in Wistar Rats

It is suggested that ethanolic extract of A. esculentus exerts a dose-related gastroprotective and ameliorative effect against phenylhydrazine-induced gastric injury, supporting its potential as a dietary adjunct in the management of oxidative gastric mucosal damage.

E. O. Nweke, Benedict Onyekachukwu Ekwuno, A. Obi et al. · 1 citation
Open access Aug 2026

Effect of Ethanolic Extract of Curcuma longa (Turmeric) on Body Weight and Relative Testicular Weight in Lead Acetate-Induced Toxicity in Adult Male Wistar Rats

Ethanolic Curcuma longa extract at 400 mg/kg was associated with a significant increase in body weight in lead-exposed rats, suggesting a possible beneficial systemic effect, however, relative testicular weight was not significantly altered.

E. O. Nweke, Emmanuel Chimagoziwom Prince, A. Obi et al. · 4 citations
Open access Aug 2026

Protective Effects of Ethanolic Extract of Curcuma longa (Turmeric) on Sperm Quality and Testicular Histology Following Lead Acetate-Induced Testicular Toxicity in Adult Male Wistar Rats

Ethanolic C. longa extract produced variable effects on sperm quality and testicular histology following lead exposure, with some favorable changes particularly at 200 mg/kg, however, persistent abnormalities indicate that these effects were not uniformly dose-dependent.

E. O. Nweke, Emmanuel Chimagoziwom Prince, A. Obi et al. · 1 citation

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