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A. Pensado-López

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Oct 2026

Systemic administration of poly(I:C) and resiquimod reprograms tumor-associated macrophages and prevents tumor progression and metastasis in murine cancer models.

Tumor-associated macrophages (TAMs) drive the immunosuppressive tumor microenvironment (TME), promoting oncogenic progression, metastasis and treatment resistance. While we previously established that intratumoral administration of poly(I:C) and R848 (TLR3 and TLR7/8 agonists) has strong therapeutic efficacy and trigge...

Clément Anfray, A. Pensado-López, F. Castro et al. · 0 citations
Open access Jul 2026

Unraveling the impact of trip12 on neurodevelopment: insights from a zebrafish model

This study provides substantial evidence for the vital role of trip12 in the early stages of development, as homozygous individuals exhibited early mortality by Day 23 post-fertilization, while a substantial mortality rate was observed by Day 35 in ‘heterozygous’ mutants.

Maider Roibás-Santos, P. Suarez-Bregua, J. Rotllant et al. · 0 citations

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