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Annette Peters

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Open access Oct 2026

Intraindividual longitudinal changes of the proteome reveal dynamic markers of biological aging

Proteomic aging clocks have emerged as biomarkers of aging, but most rely on cross-sectional data. Here, we present a proteomic aging clock based on longitudinal measurements of liquid chromatography–mass spectrometry plasma proteomics at up to three time points in the population-based KORA cohort, comprising 9,105 sam...

R. Lermer, X. Qian, S. Pusch et al. · 0 citations
Open access Sep 2026

Do Androgens and Sex Hormone-Binding Globulin Mediate Sex Differences in the Risk of Stroke and Myocardial Infarction? The KORA Study.

BACKGROUND Sex differences in cardiovascular disease are well established, but the role of androgens and sex hormone-binding globulin (SHBG) remains unclear. We investigated whether these hormones and SHBG mediate sex differences in the risk of stroke and myocardial infarction (MI). METHODS Observational data from th...

H. Raeisi-Dehkordi, Mojgan Amiri, B. Thorand et al. · 0 citations
Open access Aug 2026

Differential associations of resting heart rate and heart rate variability indices with cardiovascular and coronary heart disease mortality risk: the prospective KORA study

Limited data exist on the relationship of resting heart rate (RHR) and heart rate variability (HRV) indices with cardiovascular (CVD) and coronary heart disease (CHD) mortality in individuals with and without (pre)diabetes. We investigated overall and glucose tolerance status-specific association of RHR and a large num...

K. Oluwagbemigun, Dan Ziegler, Alexander Strom et al. · 0 citations
Jul 2026

Association of long-term exposure to air pollution, built environment and air temperature with the incidence of prediabetes phenotypes, and prediabetes remission and progression to type 2 diabetes: a longitudinal study in the KORA cohort

Air pollutants and the built environment with iIGT or IFG+IGT are associated with increased incidence of IGT and decreased remission of iIFG, and co-exposure to environmental mixtures was associated with increased risks of iIFG, iIGT and IFG+IGT.

Yue Xi, B. Thorand, Alexandra Schneider et al. · 0 citations

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