This work explores structure-based strategies to identify small-molecule agonists of neurotensin (NTS) receptors, leading to the discovery of potent agonists with in vivo antinociceptive effects and to insights into the molecular basis of receptor activation.
Nicolas Panel, D. D. Vo, Harald Hübner et al.· Nature Communications· 0 citations
Protein engineering appears to be entering a golden age, defined by a rapidly accelerating pace of progress, even as significant challenges in design, screening, and real-world application remain.
H. Ai, Frances H. Arnold, Doug Barrick et al.· Protein engineering, design...· 0 citations
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