Open access
Aug 2026
Integrated computational and preclinical evaluation of drug repurposing candidates for KRAS-mutant non-small cell lung cancer
Findings support nilotinib as a promising therapeutic candidate for KRAS-mutant NSCLC after a structure-based drug repurposing approach was employed to screen FDA-approved compounds targeting key regulators to the MAPK signalling pathway.
Anisha Jain, Chandan Dharmashekar, B. S et al.
· Scientific Reports · 0 citations