Oct 2026
B-216 Validation and Optimization of AAV9 Total Antibody Testing in Gene Therapy
Adeno-associated virus serotype 9 (AAV9) is widely used as a gene therapy vector. Pre-existing anti-AAV9 antibodies can reduce transduction efficiency and pose safety risks, making accurate antibody detection essential for patient selection and immune monitoring. However, despite its importance, current laborator...
Jing-Cai Wang, K. Everhart, Dean A. Lee et al.
· Clinical Chemistry · 0 citations