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Author

A. R. Subramaniam

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Open access Oct 2026

tRNA dosage regulates lineage dependency and resistance in prostate cancer.

Lineage plasticity underlies therapeutic resistance in cancer1,2, yet the translational mechanisms that enable this phenotypic flexibility remain largely unknown. Here using prostate cancer as a model of lineage dependence, we performed unbiased small RNA sequencing and identified tRNA1Arg(UCU) as a regulator of lineag...

Y. Kim, Sonali Arora, D. Young et al. · 0 citations

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