Bacterial surface layer ⸻ Properties, role, applications and challenges ⸻ A review of the next-generation nanotechnological tool.
Surface-layer (S-layer) proteins, forming the outermost envelope of many bacteria and archaea, exhibit extraordinary structural precision and self-assemble into two-dimensional crystalline lattices with square, hexagonal, or oblique symmetry. These monomolecular arrays, typically 5 to 25 nm in periodicity (varying by s...