Immunogenicity, Reactogenicity, and Safety of CRM197-Conjugated Meningococcal A, C, W, Y Vaccine: Multicenter, Randomized, Phase III Trial
Background . Generalized forms of meningococcal disease caused by Neisseria meningitidis are characterized by rapid course and high mortality. The pathogen serogroup distribution varies between regions and changes over time, which determines the need for vaccines covering currently relevant serogroups A, C, W and Y....