A. S. L. Mendez

In Vitro Dissolution Profile of Nitazoxanide Oral Suspension: Applying an HPLC Method in Drug Solubility and Chemical Stability Studies, With a Direct Impact on In Vitro Release

Nitazoxanide is a broad‐spectrum prodrug widely used against protozoa, helminthes, and anaerobic bacteria. Due to its hydrophobicity, this drug exhibits limited water solubility, making its release from the formulation critical. Furthermore, its rapid degradation into tizoxanide (the in vivo active form) requires a...