A. S. V. van Irsen

Activation of D2-Expressing Medium Spiny Neurons in the Nucleus Accumbens Core Mirrors the Delaying Effect of Novelty Exposure on Feeding Onset in Rats

These findings suggest that NAcc D2-MSNs are recruited under conditions of environmental novelty to modulate feeding-related decision-making, and may impair behavioral flexibility and contribute to maladaptive feeding patterns, with implications for the neurobiology of eating disorders.