Author

A. S. Yatsenko

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Open access Oct 2026

Argonaute 1 associates with nucleolar snoRNP machinery and regulates pre-rRNA levels and cell growth

Argonaute proteins are best known as cytoplasmic effectors of small-RNA-mediated gene silencing, although their compartment-specific functions remain incompletely understood. Here, we identify a previously unrecognized nucleolar role for Drosophila Argonaute 1 (AGO1). We observed stress-induced redistribution of AGO1 i...

Rucha Y. Hebalkar, Nils Schumann, A. S. Yatsenko et al. · bioRxiv · 0 citations

Open access Aug 2026

A conserved serotonin receptor pathway is a druggable modifier of Tau pathology, neural circuit formation and neurodegeneration

A new Drosophila tauopathy model expressing eGFP-tagged human TauWT or the disease-associated TauP301L variant in the nervous system is established and 5-HT7R signaling is identified as a conserved and druggable modifier of Tau toxicity.

Mariana I. Tsap, Valeriya V. Navrotska, J. Labus et al. · bioRxiv · 0 citations